Author

John S. Crabb

Cleveland Clinic

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Biochemistry· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Assay:proteomics· 1

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Allison GrenelliD· 1 shared Alyson WolkiD· 1 shared Bela Anand‐ApteiD· 1 shared Charandeep SinghiD· 1 shared Courtney E. HershbergeriD· 1 shared Geeng-Fu Jang· 1 shared Jianhai DuiD· 1 shared John W. Crabb· 1 shared

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Allison GrenellORCID

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1 paper

Recent·Most cited

BiochemistryMolecular MetabolismPeer-reviewedJul 22, 2024

Tissue Inhibitor of Metalloproteinase 3 (TIMP3) mutations increase glycolytic activity and dysregulate glutamine metabolism in RPE cells

Allison Grenell, Charandeep Singh, Monisha Raju…·Bela Anand‐Apte

This study shows that TIMP3 mutations in RPE cells increase glycolytic activity and disrupt glutamine metabolism, linking these changes to Sorsbys Fundus Dystrophy.

5 citations

humanmouse

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