In vivo lineage conversion of vertebrate muscle into early endoderm-like cells
Clyde Allen Campbell, Joseph J. Lancman, Raquel Espín Palazón, Jonatan Matalonga, Jiaye He, Alyssa L. Graves, Xin-Xin I. Zeng, Rashmi Mishra, Jan Huisken, David J. Traver, P. Duc Si Dong
This study shows that differentiated zebrafish muscle cells can be reprogrammed into endoderm-like cells in vivo through Sox32 and Oct4 co-expression, challenging previous assumptions about lineage restriction.
bioRxiv · Aug 9, 2019 · PreprintDevelopmental Biology