Author

Clyde Allen Campbell

Iowa State UniversityORCID 0000-0002-0619-9247Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Organism:zebrafish· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Raquel Espín-PalazóniD· 2 shared Xiaoyi Cheng· 2 shared A FidanzaiD· 1 shared Abigail Gorden· 1 shared Alyssa L. Graves· 1 shared Brandon HadlandiD· 1 shared Cole TrapnelliD· 1 shared David J. TraveriD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersDevelopmental Biology

Raquel Espín-PalazónORCID

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3 papers

Recent·Most cited

Developmental regulation of endothelial-to-hematopoietic transition from induced pluripotent stem cells

Rachel Wellington, Xiaoyi Cheng, Shuvra Dutta, Clyde Allen Campbell, Cole Trapnell, Raquel Espín-Palazón, Brandon Hadland, Sergei R. Doulatov

The paper maps single-cell dynamics of endothelial-to-hematopoietic transition from iPSCs and identifies FGF signaling modulation to improve hematopoietic output.

Stem Cell Reports · Sep 23, 2025Peer-reviewedDevelopmental Biology

Nod1-dependent NF-kB activation initiates hematopoietic stem cell specification in response to small Rho GTPases

Xiaoyi Cheng, Radwa Barakat, Giulia Pavani, Masuma Khatun Usha, Rodolfo Calderon, Elizabeth M. Snella, Abigail Gorden, Yudi Zhang, Paul J. Gadue, Deborah L. French, Karin S. Dorman, A Fidanza, Clyde Allen Campbell, Raquel Espín-Palazón

This paper identifies the NOD1-RIPK2-NFkB axis as a critical inflammatory pathway for hematopoietic stem cell specification from human pluripotent stem cells.

Nature Communications · Nov 23, 2023Peer-reviewedDevelopmental Biology

In vivo lineage conversion of vertebrate muscle into early endoderm-like cells

Clyde Allen Campbell, Joseph J. Lancman, Raquel Espín Palazón, Jonatan Matalonga, Jiaye He, Alyssa L. Graves, Xin-Xin I. Zeng, Rashmi Mishra, Jan Huisken, David J. Traver, P. Duc Si Dong

This study shows that differentiated zebrafish muscle cells can be reprogrammed into endoderm-like cells in vivo through Sox32 and Oct4 co-expression, challenging previous assumptions about lineage restriction.

bioRxiv · Aug 9, 2019 · PreprintDevelopmental Biology