Author

Jonathan L. Papa

The Ohio State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Adriana ForeroiD· 2 shared Jack E. RoettgeriD· 2 shared Jacob S. YountiD· 2 shared Matthew I. McFaddeniD· 2 shared Benjamin Douglas Xun LiuiD· 1 shared Brendan M. Reznik· 1 shared Jana M. CableiD· 1 shared Parker J. DenziD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Adriana ForeroORCID

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2 papers

Recent·Most cited

Gasdermin E is Dispensable for H1N1 Influenza Virus Pathogenesis in Mice

Samuel Speaks, Jonathan L. Papa, Matthew I. McFadden, Jack E. Roettger, Benjamin Douglas Xun Liu, Shreenath Mohan, Brendan M. Reznik, Steve Leumi, Jana M. Cable, Adriana Forero, Jacob S. Yount

This study shows that gasdermin E is not essential for H1N1 influenza virus pathogenesis in mice, as Gsdme-/- mice exhibit similar infection outcomes to wild-type mice.

Microbiology Spectrum · Feb 5, 2026Peer-reviewedImmunology

Accelerated Adaptation of SARS-CoV-2 Variants in Mice Lacking IFITM3 Preserves Distinct Tropism and Pathogenesis

Parker J. Denz, Jonathan L. Papa, Matthew I. McFadden, Prerana R. Rao, Jack E. Roettger, Adriana Forero, Jacob S. Yount

This study shows that IFITM3 deficiency accelerates SARS-CoV-2 adaptation in mice, revealing how variant traits influence tropism and pathogenesis across hosts.

bioRxiv · Jan 27, 2025 · PreprintImmunology