The Mlh1-Pms1 endonuclease uses ATP to preserve DNA discontinuities as strand discrimination signals to facilitate mismatch repair
Jonathan M. Piscitelli, Scott J. Witte, Yasmine S. Sakinejad, Carol M. Manhart
This paper shows that the Mlh1-Pms1 endonuclease uses ATP binding to recognize DNA discontinuities, preserving them as strand discrimination signals for mismatch repair.
Nucleic Acids Research · Dec 19, 2024Peer-reviewedBiochemistry