Author

Josefine Jakob

Goethe University Frankfurt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Thomas OellerichiD· 2 shared Adarsh M. KumariD· 1 shared Aimo KanntiD· 1 shared Amirhossein Barati SedehiD· 1 shared Arne Hackspacher· 1 shared Astrid Brüggerhoff· 1 shared Astrid Kaiser· 1 shared Bernhard BrüneiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Thomas OellerichORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 28, 2026

Extracellular protein catabolism drives regulated nitrogen handling and ammonia buffering in acute myeloid leukemia

Nina Kurrle, Philipp Makowka, Vera Schlipfenbacher…·Hubert L. Serve

This study shows AML cells use extracellular protein catabolism to supply amino acids and manage nitrogen, with GS/GLUL playing a key role in ammonia buffering and disease progression.

DOI 10.64898/2026.08.27.747222

humanproteomics

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BiochemistryJournal of Medicinal ChemistryPeer-reviewedJun 18, 2025

STRUCTURE-BASED DESIGN OF PROTACS FOR THE DEGRADATION OF SOLUBLE EPOXIDE HYDROLASE

Julia Schönfeld, Steffen Brunst, Ludmila Ciomirtan…·Kerstin Hiesinger

This paper designs and tests sEH-PROTACs to degrade soluble epoxide hydrolase, identifying PROTAC 23 as effective in degrading sEH in human macrophages.

11 citations

humanprotein structure

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