Author

Joseph Colin Kern

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Assay:scATAC-seq· 3 Assay:scRNA-seq· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2

Frequent Co-Authors

Ariana S. BarcomaiD· 3 shared Bing ReniD· 3 shared Cindy Tatiana Báez-Becerra· 3 shared Jackson K. Willier· 3 shared Jacqueline OlnessiD· 3 shared Jessica Arzavala· 3 shared Jonathan A. RinkiD· 3 shared Joseph R. EckeriD· 3 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Ariana S. BarcomaORCID

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Author profile →

3 papers

Recent·Most cited

A Multimodal Single-Cell Epigenomic and 3D Genome Atlas of the Human Basal Ganglia

Wubin Ding, Amit Klein, Cindy Tatiana Báez-Becerra, Jonathan A. Rink, Anna Bartlett, Ruoxuan Wang, Qiurui Zeng, Rosa Castanon, Joseph R. Nery, Emma Osgood, William S. Owens, Alaina Petrella, Chumo Chen, Andrea Saldana Acerbo, Ariana S. Barcoma, , Joseph R. Ecker

This paper creates a multimodal single-cell atlas of the human basal ganglia, revealing epigenomic and 3D genome features across cell types and linking them to disease-associated genetic risk.

bioRxiv · Jun 23, 2026 · PreprintNeuroscience

Single-Cell Epigenomics Uncovers Heterochromatin Instability and Transcription Factor Dysfunction during Mouse Brain Aging

Maria Luisa Amaral, Sainath Mamde, Michael Miller, Xiaomeng Hou, Jessica Arzavala, Julia K. Osteen, Nicholas D. Johnson, Elizabeth W. Smoot, Qian Yang, Emily R. Eisner, Qiurui Zeng, Cindy Tatiana Báez-Becerra, Jacqueline Olness, Joseph Colin Kern, Jonathan A. Rink, , Bing Ren

The paper uses single-cell epigenomics to study brain aging in mice, finding heterochromatin instability and transcription factor dysfunction across multiple brain regions and cell types.

Cell Reports · Mar 1, 2026Peer-reviewedGenomics

Single-cell Multiome Analysis of Chromatin State and Transcriptome in the Human Basal Ganglia

Lei Chang, Kai Li, Yang Xie, Guojie Zhong, Jonathan A. Rink, Cindy Tatiana Báez-Becerra, Anita Lie, Hannah S. Indralingam, Keyi Dong, Timothy H. Loe, Zhaoning Wang, Songpeng Zu, Joseph Colin Kern, Zoey Zhao, Eric Boone, , Bing Ren

This paper presents a single-cell multiome atlas of the human basal ganglia, linking chromatin states and transcriptomes to cell-type identity and disease-associated variants.

bioRxiv · Feb 4, 2026 · PreprintGenomics