Author

Anita Lie

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 2 Genomics· 2

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 4 Organism:human· 4 Assay:scRNA-seq· 4 Assay:scATAC-seq· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:differential expression· 2

Frequent Co-Authors

Bing ReniD· 4 shared Timothy H. Loe· 4 shared Ting WangiD· 4 shared Jacinta D. LuceroiD· 3 shared Yang XieiD· 3 shared Zhaoning WangiD· 3 shared Agnieszka D’Antonio‐ChronowskaiD· 2 shared Aleksandra Bikkina· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersGenomics

Bing RenORCID

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4 papers

Recent·Most cited

Single-cell Multiome Analysis of Chromatin State and Transcriptome in the Human Basal Ganglia

Lei Chang, Kai Li, Yang Xie, Guojie Zhong, Jonathan A. Rink, Cindy Tatiana Báez-Becerra, Anita Lie, Hannah S. Indralingam, Keyi Dong, Timothy H. Loe, Zhaoning Wang, Songpeng Zu, Joseph Colin Kern, Zoey Zhao, Eric Boone, , Bing Ren

This paper presents a single-cell multiome atlas of the human basal ganglia, linking chromatin states and transcriptomes to cell-type identity and disease-associated variants.

bioRxiv · Feb 4, 2026 · PreprintGenomics

Single-Cell Atlas of Transcription and Chromatin States Reveals Regulatory Programs in the Human Brain

Yang Xie, Lei Chang, Guojie Zhong, Jonathan A. Rink, Tatiana Baez-Becerra, Ethan J. Armand, Wubin Ding, Kai Li, Éric Bonne, Anita Lie, Hannah S. Indralingam, Keyi Dong, Timothy H. Loe, Bohan Huang, Zhaoning Wang, , Bing Ren

The paper creates a single-cell atlas of transcription and chromatin states in the human brain, identifying regulatory programs and linking them to neuropsychiatric disorders.

bioRxiv · Feb 3, 2026 · PreprintGenomics

Single cell multiomics reveals drivers of metabolic dysfunction-associated steatohepatitis

Weston S. Elison, Lei Chang, Yang Xie, Charlene Miciano, Qian Yang, Hannah M Mummey, Ryan Lancione, Sierra Corban, Sadatsugu Sakane, Jacinta D. Lucero, Sainath Mamde, Hyun Sik Kim, Matthew J Kim, Rebecca L. Melton, Luca Tucciarone, , Kyle J. Gaulton

This study uses single-cell multi-omics to identify cell type-specific regulatory networks and novel therapeutic targets in MASLD.

medRxiv · May 9, 2025 · PreprintGenetic & Genomic Medicine

Single cell multiomics and 3D genome architecture reveal novel pathways of human heart failure

Yang Xie, Luca Tucciarone, Elie N. Farah, Lei Chang, Qian Yang, Thirupura Sundari Shankar, Weston S. Elison, Shaina Tran, Jovina Djulamsah, Anita Lie, Timothy H. Loe, Alyssa R. Holman, Sierra Corban, Justin Buchanan, Sainath Mamde, , C. Neil

The paper integrates single-cell multi-omics and 3D genome data from human hearts to identify gene regulatory changes and causal genetic contributors in heart failure.

medRxiv · May 8, 2025 · PreprintGenetic & Genomic Medicine