Artificial intelligence-enabled automated analysis of transmission electron micrographs to evaluate chemotherapy impact on mitochondrial morphology in triple negative breast cancer
Argenis Arriojas, Mokryun L. Baek, Mariah J. Berner, Jiaqi Wang, Joseph Duraisingh, Alexander Zhurkevich, Antentor Othrell Hinton Jr., Matthew D. Meyer, Lacey Elizabeth Dobrolecki, Michael T. Lewis, Kourosh Zarringhalam, Gloria Vittone Echeverria
The paper introduces an AI model to analyze mitochondrial morphology in TNBC using TEM images, finding significant structural changes in response to chemotherapy and metastasis.
bioRxiv · Feb 19, 2025 · PreprintCancer Biology