Author

Joseph Neos Cruz

Max Planck Institute for Multidisciplinary Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Organism:human· 1 Research Focus:transcription & RNA processing· 1

Frequent Co-Authors

A. Marieke OudelaariD· 1 shared Abrar AljahaniiD· 1 shared Jackson M. GordoniD· 1 shared Karla M. NeugebaueriD· 1 shared Magdalena A. KarpińskaiD· 1 shared Michael LidschreiberiD· 1 shared Shyam RamasamyiD· 1 shared T. B. Ngoc CaoiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 22 mutual co-author links

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1 shared paperMolecular Biology

A. Marieke OudelaarORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintMay 4, 2026

Efficient co-transcriptional splicing enforces rapid microexon definition and inclusion by SRRM4

Jackson M. Gordon, Joseph Neos Cruz, Karla M. Neugebauer

The paper investigates how SRRM4 facilitates efficient co-transcriptional splicing of microexons, showing that upstream intron removal enables rapid microexon inclusion in neurons.

DOI 10.64898/2026.05.02.722430

humanbulk RNA-seq

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Molecular BiologyNature Structural & Molecular BiologyPeer-reviewedJul 1, 2023

The Mediator complex regulates enhancer-promoter interactions

Shyam Ramasamy, Abrar Aljahani, Magdalena A. Karpińska…·A. Marieke Oudelaar

This study shows that the Mediator complex is essential for enhancer-promoter interactions, as its depletion reduces interaction frequencies and gene expression, while increasing CTCF-binding site interactions and altering Cohesin distribution.

127 citationstop 1%

ChIP-seqexperimental assay

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