Nuclear stress bodies enable a germline-specific transcriptional stress response in Drosophila
Dhanashree Lakhe, Lorenzo Gallicchio, Juan Sebastian Ochoa Gutierrez, Joshua Duering, Demir Erensoy, Franziska Brändle, Anna Sintsova, John M. Franklin, Madhav Jagannathan
This study identifies nuclear stress bodies in Drosophila germline that mediate a stress response by delaying Hsf-dependent transcription and enabling selective expression of molecular chaperones over transposable elements.
bioRxiv · Aug 25, 2026 · PreprintCell Biology