Dhanashree Lakhe

Protein-driven colloid-osmotic pressure controls nuclear size, organization, and function

The paper shows that protein-driven osmotic pressure regulates nuclear size and function, affecting chromatin organization and gene expression in yeast, human, and fly cells.

Nuclear stress bodies enable a germline-specific transcriptional stress response in Drosophila

This study identifies nuclear stress bodies in Drosophila germline that mediate a stress response by delaying Hsf-dependent transcription and enabling selective expression of molecular chaperones over transposable elements.