David N. Linsenbardt

This study investigates sex-specific behavioral predictors of alcohol consumption by remotely presenting alcohol-predicting cues and analyzing correlations between behaviors and drinking variables.

The paper identifies epileptiform discharges as a critical feature in a preclinical model of FASD, showing their relationship to high-frequency oscillations in the retrosplenial cortex.

The paper uses in vivo electrophysiology and dimensionality reduction to show alcohol exposure reduces firing rates in thalamic neurons but increases hippocampal excitability in mice.

This study shows that female mice, but not males, experience reduced corticostriatal theta coherence after repeated binge alcohol drinking.

The paper investigates how ethanol exposure disrupts neuronal networks involved in fear memory in mice, finding hyperconnectivity in the limbic system and altered Fos+ neuron activity.

The paper identifies neural signatures of resource-based and resistance-based cognitive control in rats during delay discounting tasks using electrophysiological recordings.

This study examines how different patterns of maternal alcohol consumption during pregnancy affect offspring neurobehavioral outcomes in mice.

This study shows that knocking out NSG2 enhances associative learning and cognitive flexibility without affecting motor or affective behaviors.

This study identifies gene expression changes in brain tissue following spreading depolarization, showing activation of pathways related to cell differentiation, synaptic plasticity, and neuroprotection.

This study shows that dmPFC encoding changes with delay duration, reflecting deliberative processes at longer delays and impulsive choices at shorter delays.

This study investigates how different rodent diets affect ethanol front-loading in mice, finding that LabDiet 5001 leads to higher blood ethanol concentrations and front-loading compared to Teklad 2920x, with front-loading persisting after diet switch.

This study shows that alcohol preferring P rats continue to drink alcohol mixed with quinine despite aversion, unlike Wistar rats, suggesting a genetic basis for aversion-resistant drinking.

This study shows that rats with a family history of excessive drinking show reduced neural activity in the prefrontal cortex associated with the intention to drink alcohol.