Massively Parallel Profiling of RNA-targeting CRISPR-Cas13d
Hung‐Che Kuo, Joshua Prupes, Chia‐Wei Chou, Ilya J. Finkelstein
The paper introduces RNA-CHAMP, a platform to measure RNA binding specificity of CRISPR-Cas13d, revealing structural and sequence determinants of target recognition and enabling SNP detection in SARS-CoV-2 variants.
Nature Communications · Jan 12, 2024Peer-reviewedMolecular Biology