Coordination of Anle138b to Silver Results in Selective Reduction of a C-terminal truncated Alpha-synuclein Protein and Increased Aggregate Size
Kelly L. Rue, Susana Herrera, Zhichun Shi, Indranil Chakraborty, Jeremy Tachiki, Josue Ballesteros, Julie Kay Andersen, Gordon J. Lithgow, Wisam A. Al Isawi, Gellert Mezei, Minna Schmidt, Raphael G. Raptis
The paper investigates how Anle138b coordination with silver affects alpha-synuclein aggregation, showing reduced C-terminal truncation and increased aggregate size.
ChemMedChem · Apr 9, 2026Peer-reviewedBiochemistry