Early Exposure to Polycyclic Aromatic Hydrocarbons (PAHs) and Cardiac Toxicity in a Species (Xenopus laevis) with Low Aryl Hydrocarbon Receptor (AHR) Responsiveness
Madison C. Sestak, Julia A. Pinette, Caithlin M. Lamoureux, Susan L. Whittemore
This study examines the cardiac toxicity of PAHs in Xenopus laevis, finding that PHE, PYR, and FLA impair cardiac function and increase cyp1a expression, while BaP effects are AHR-dependent.
bioRxiv · Apr 16, 2018 · PreprintPharmacology & Toxicology