PhysiologybioRxivPreprint
Systemic inhibition of de novo purine biosynthesis prevents weight gain and improves metabolic health by increasing thermogenesis and decreasing food intake
Jacob W. Myers, Woo Yong Park, Alex M. Eddie…·Elma Zaganjor
This study shows that inhibiting purine biosynthesis with mizoribine prevents weight gain and improves metabolic health in mice on a high-fat diet by increasing thermogenesis and reducing food intake.
3 citations