Matrimeres are systemic nanoscale mediators of tissue integrity and function
Koushik Debnath, Irfan Qayoom, Steven O’Donnell, Julia Ekiert, Can Wang, Mark A. Sanborn, Chang Liu, Ambar Rivera, Ik Sung Cho, Saiumamaheswari Saichellappa, Péter T. Tóth, Dolly Mehta, Jalees Rehman, Xiaoping Du, Yu Gao, Jae‐Won Shin
The paper identifies matrimeres as nanoscale mediators of tissue integrity, showing they can restore vascular integrity after injury and are reconstituted from fibronectin, DNA, and acidic conditions.
bioRxiv · Mar 25, 2024 · PreprintBioengineering