Cdk1 and PP2A constitute a molecular switch controlling orderly degradation of atypical E2Fs
Sapir Nachum, Noy Gamliel, Danit Wasserman, Nasrin Qassem, Inbal Sher, Julia Guez-Haddad, Michael J. Emanuele, Jordan H. Chill, Amit Tzur
The paper identifies Cdk1 and PP2A as a molecular switch that controls the degradation of E2F7 and E2F8, ensuring timely transcriptional reprogramming during the cell cycle.
Molecular Biology of the Cell · Aug 12, 2026Peer-reviewedCell Biology