Lipoprotein(a) promotes thrombosis through platelet activation and promotion of a lysis-resistant thrombus architecture
Justin R. Clark, Frances S. K. Sutherland, Julia M. Assini, Arnaud S. Girard, Sébastien Thériault, Benoît J. Arsenault, Marlys L. Koschinsky, Michael B. Boffa
This study shows that lipoprotein(a) promotes thrombosis by enhancing platelet activation and creating lysis-resistant thrombus structures, with effects mitigated by aspirin.
bioRxiv · Jul 30, 2026 · PreprintBiochemistry