The stem cell-specific protein TRIM71 inhibits maturation and activity of the pro-differentiation miRNA let-7 via two independent molecular mechanisms
Lucia Torres Fernández, Sibylle Mitschka, Thomas Ulas, Stefan Christopher Weise, K. Dahm, Matthias Becker, Kristian Händler, Marc Beyer, Julia Windhausen, Joachim Ludwig Schultze, Waldemar Kolanus
This study identifies two independent mechanisms by which TRIM71 inhibits let-7 miRNA maturation and activity, impacting developmental and oncogenic processes.
RNA · May 11, 2021Peer-reviewedMolecular Biology