Identifying in vivo genetic dependencies of melanocyte and melanoma development
Sarah C. Perlee, Yilun Ma, Miranda V. Hunter, Jacob B Swanson, Nelly M. Cruz, Zhitao Ming, Julia Xia, Timothée Lionnet, Maura McGrail, Richard Mark White
This study uses a zebrafish model to identify genetic dependencies in melanocyte and melanoma development, revealing that gene loss can paradoxically promote aggressive phenotypes.
eLife · Aug 7, 2025Peer-reviewedGenetics