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Juliane S Müller

University of Cambridge

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Neuroscience· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

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András LakatosiD· 1 shared Camilla LyonsiD· 1 shared Daniel LagosiD· 1 shared Denisa HathaziiD· 1 shared Éva MoravaiD· 1 shared Huw W. NayloriD· 1 shared İbrahim ElsharkawiiD· 1 shared Irena Josephina Johanna MuffelsiD· 1 shared

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1 paper

Recent·Most cited

NeuroscienceDOAJ (DOAJ: Directory of Open Access Journals)Peer-reviewedJun 21, 2026

Mitochondrial DNA heteroplasmy drives cortical neuronal disturbances in human organoids harbouring the common m.3243A>G mutation

Denisa Hathazi, Camilla Lyons, Daniel Lagos…·Rita Horváth

This study shows that high mitochondrial DNA heteroplasmy in human organoids with the m.3243A>G mutation causes cortical neuronal disturbances, including axonal degeneration and apoptosis, similar to MELAS patients.

DOI 10.1038/s41467-026-74103-y

humanbulk RNA-seq

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