Restoring Glutamate receptosome dynamics at synapses rescues Autism-like deficits in Shank3-deficient mice.
Enora Moutin, Sophie Sakkaki, Vincent Compan, Nathalie Bouquier, Federica Giona, Julie Areias, Elise Goyet, Anne-Laure Hemonnot-Girard, Vincent Seube, Bastien Glasson, Nathan Bénac, Yan Chastagnier, Fabrice Raynaud, Étienne Audinat, Laurent Groc, , Julie Perroy
This study shows that restoring glutamate receptosome dynamics in Shank3-deficient mice rescues synaptic and behavioral deficits associated with autism.
Molecular Psychiatry · Jul 30, 2021Peer-reviewedNeuroscience