Heterogeneity of normal human breast stem and progenitor cells as revealed by transcriptional profiling
Justin A. Colacino, Ebrahim Azizi, Michael D. Brooks, Ramdane A Harouaka, Shamileh Fouladdel, Sean McDermott, Michael Lee, David R. Hill, Julie M. Madden, Julie L. Boerner, Michele L. Coté, Maureen A. Sartor, Laura S. Rozek, Max S. Wicha
The paper uses single-cell RNA sequencing to analyze ALDH+ and CD44+CD24- populations in normal human breast tissue, revealing heterogeneity and hybrid epithelial/mesenchymal cells with stemness and EMT features.
Stem Cell Reports · Mar 29, 2018Peer-reviewedDevelopmental Biology