Julie L. Boerner

LevenMap is a new small RNA-sequencing alignment tool that outperforms existing aligners in mapping reads to non-coding RNA databases.

This paper identifies a TGF-β/S100A9/CXCR2 axis in metastatic TNBC that drives neutrophil expansion and immune suppression, with S100A9 loss enhancing immunotherapy response.

This study shows that combining Menin and XPO1 inhibitors synergistically inhibits KMT2A-r and NPM1-m AML cell growth and improves survival in xenograft models.

This study examines the relationship between genetic ancestry, somatic mutation frequency, and histologic subtypes in high-grade endometrial cancer, finding associations between local ancestry and tumor mutation burden and histologic subtypes.

The paper uses single-cell RNA sequencing to analyze ALDH+ and CD44+CD24- populations in normal human breast tissue, revealing heterogeneity and hybrid epithelial/mesenchymal cells with stemness and EMT features.