Physical and functional convergence of the autism risk genes Scn2a and Ank2 in neocortical pyramidal cell dendrites
Andrew D. Nelson, Amanda M. Catalfio, Julie P. Gupta, Lia Y. Min, René N. Caballero-Florán, Kendall P. Dean, Carina C. Elvira, Kimberly D. Derderian, Henry Kyoung, Atehsa Sahagun, Stephan Sanders, Kevin J. Bender, Paul M. Jenkins
This study shows that Ank2 and Scn2a work together in dendrites of neocortical neurons, linking their dysfunction to autism spectrum disorder.
Neuron · Jan 29, 2024Peer-reviewedNeuroscience