Sex-specific thermoregulatory effects of estrogen signaling in Reprimo lineage cells
Jae W. Park, Laura R. Cortes, Norma P. Sandoval, Adriana R Vree, Alejandra G Baron, Kelly A. Vranich, Higor J Fideles, Rosalizbeth M. Martinez, Elizabeth A. Dilday, Mia R. Hansen, Weronika Budek, Julissa I Lopez, Laura G. Kammel, J. Edward van Veen, Stephanie M. Correa
This study shows estrogen signaling in Reprimo lineage cells affects thermoregulation in female mice by altering brown adipose tissue thermogenesis, but not in males.
Endocrinology · Nov 27, 2025Peer-reviewedPhysiology