Nonenzymatic, prebiotic aminoacylation couples chirality of RNA and protein
Joshua A. Davisson, Evan M. Kalb, Shangsi Lin, Jungyeon Lee, Isaac J. Knudson, Alanna Schepartz, Aaron E. Engelhart, Shenglong Zhang, Katarzyna P. Adamala
This paper demonstrates a prebiotic, nonenzymatic aminoacylation process that couples RNA and protein chirality, favoring opposite L- and D- configurations.
ACS Omega · Jul 10, 2026Peer-reviewedBiochemistry