Heterologous immunization modulates B-cell epitope competition between helper peptides and the MPER segment in MPER/liposome vaccines
Rafiq Ahmad Khan, Junjian Chen, Luke R. Donius, Ellis L. Reinherz, Mikyung Kim
This study shows that heterologous boosting enhances MPER-specific B cell responses in MPER/liposome vaccines by increasing B cell affinity and reducing competition from helper peptides.
npj Vaccines · Jan 16, 2026Peer-reviewedImmunology