Heterologous immunization modulates B-cell epitope competition between helper peptides and the MPER segment in MPER/liposome vaccines
Rafiq Ahmad Khan, Junjian Chen, Luke R. Donius…·Mikyung Kim
This study shows that heterologous boosting enhances MPER-specific B cell responses in MPER/liposome vaccines by increasing B cell affinity and reducing competition from helper peptides.