Geographical variation drives adaptive equilibrium of the P. falciparum sickle-associated mutations
André Python, Annie J. Forster, Peter Martin Todd, Karamoko Niaré, Melissa D. Conrad, Lucas Naam-Kayagre Amenga-Etego, Deus S. Ishengoma, Jianjun Lian, Baoli Liu, Yucheng Yan, Jingmin Liang, Muhammad M. Khan, Junkan Zheng, Jeffrey A. Bailey, David J. Conway, , Gavin Band
The paper investigates how geographical variation influences the adaptive evolution of Plasmodium falciparum mutations that counteract sickle cell trait protection.
bioRxiv · Aug 31, 2025 · PreprintGenetics