The peroxiredoxin Tsa1 extends the lifespan of budding yeast by maintaining the stability of the ribosomal RNA gene cluster.
Junno Ohira, Mariko Sasaki, Takehiko Kobayashi
This study shows that Tsa1 stabilizes the rDNA cluster in budding yeast, preventing rDNA instability and extending lifespan.
bioRxiv · Mar 14, 2024 · PreprintMolecular Biology