GenomicsbioRxivPreprint
Accuracy, Reproducibility And Bias Of Next Generation Sequencing For Quantitative Small RNA Profiling: A Multiple Protocol Study Across Multiple Laboratories
MD Giraldez, Ryan M. Spengler, Alton Etheridge…·Muneesh Tewari
This study evaluates the accuracy, reproducibility, and bias of small RNA-seq across five protocols and nine labs, finding protocol-specific bias that can be mitigated with adapters and computational corrections.
5 citations