Author

K. A. Grant

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Research Focus:gene regulatory network inference· 4 Approach:statistical model· 4 Assay:scRNA-seq· 3 Approach:experimental assay· 2 Organism:non-human primate· 2 Organism:rat· 2

Frequent Co-Authors

I. Messaoudi· 4 shared S. A. Lewis· 4 shared B. Doratt· 2 shared B. M. Doratt· 2 shared M. B. Blanton· 2 shared S. Sureshchandra· 2 shared A. Jankeel· 1 shared C. Hoagland· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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4 shared papersImmunology

I. Messaoudi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Chronic alcohol consumption dysregulates innate immune response to SARS-CoV-2 in the lung

S. A. Lewis, I. R. Cinco, B. M. Doratt, M. B. Blanton, C. Hoagland, M. Davies, K. A. Grant, I. Messaoudi

This study shows chronic alcohol consumption reduces antiviral cytokine induction and disrupts TLR signaling in lung cells from humans and rhesus macaques infected with SARS-CoV-2.

bioRxiv · May 2, 2023Immunology

Integrated single cell analysis shows chronic alcohol drinking disrupts monocyte differentiation in the bone marrow niche

S. A. Lewis, B. M. Doratt, Q. Qiao, M. B. Blanton, K. A. Grant, I. Messaoudi

This study shows chronic alcohol consumption disrupts monocyte differentiation in the bone marrow niche, leading to heightened inflammation and compromised anti-microbial defenses in circulating monocytes.

bioRxiv · Mar 29, 2023Immunology

Chronic ethanol drinking in non-human primates induces inflammatory cathepsin gene expression in alveolar macrophages accompanied by functional defects

S. A. Lewis, B. Doratt, S. Sureshchandra, A. Jankeel, N. Newman, K. A. Grant, I. Messaoudi

This study shows chronic ethanol drinking in rhesus macaques increases inflammatory gene expression and functional defects in alveolar macrophages, linking to increased infection susceptibility.

bioRxiv · Jul 30, 2021 · PreprintImmunology

Transcriptional, epigenetic, and functional reprogramming of blood monocytes in non-human primates following chronic alcohol drinking

S. A. Lewis, S. Sureshchandra, B. Doratt, V. Jimenez, C. Stull, K. A. Grant, I. Messaoudi

This study examines how chronic alcohol drinking affects monocytes and macrophages in non-human primates, revealing hyper-inflammatory responses and impaired function.

bioRxiv · May 12, 2021Immunology