Author

K. A. Satyshur

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2

Frequent Co-Authors

B. W. Anderson· 2 shared J. D. Wang· 2 shared A. Hao· 1 shared C. Wolak· 1 shared J. Keck· 1 shared J. L. Keck· 1 shared K. Dubiel· 1 shared K. Liu· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

B. W. Anderson

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2 papers

Recent·Most cited

Molecular mechanism of regulation of the purine salvage enzyme XPRT by the alarmones pppGpp, ppGpp, and pGpp

B. W. Anderson, A. Hao, K. A. Satyshur, J. L. Keck, J. D. Wang

This study identifies how alarmones pppGpp, ppGpp, and pGpp inhibit XPRT activity by competing with PRPP, revealing structural and regulatory differences between XPRT and HPRT.

bioRxiv · Mar 4, 2020Microbiology

Evolution of (p)ppGpp-HPRT regulation through diversification of an allosteric oligomeric interaction

J. D. Wang, B. W. Anderson, K. Liu, C. Wolak, K. Dubiel, K. A. Satyshur, J. Keck

The paper identifies a conserved (p)ppGpp binding motif in HPRT across species, showing that ligand binding varies with dimer-dimer interactions that evolved to regulate purine homeostasis.

bioRxiv · Apr 28, 2019Biochemistry