Targeting Viperin to the Mitochondrion Inhibits the Thiolase Activity of the Trifunctional Enzyme Complex
A. B. Dumbrepatil, K. A. Zegalia, K. Sajja, R. T. Kennedy, E. N. G. Marsh
This paper investigates how HCMV co-opts viperin to inhibit mitochondrial thiolase activity and alter ATP levels, revealing a novel mechanism of viral immune evasion.
bioRxiv · Oct 30, 2019Biochemistry