Lipid nanodiscs as a template for high-resolution cryo-EM structures of peripheral membrane proteins
K. Cannon, R. Sarsam, T. Tedamrongwanish, K. Zhang, R. W. Baker
The paper demonstrates that lipid nanodiscs can be used to obtain high-resolution cryo-EM structures of peripheral membrane proteins, exemplified by a 3.3 Å structure of the AP2 clathrin adaptor complex.
bioRxiv · Mar 7, 2023Biochemistry