J. R. Sellers

This study reveals that myosin-5 takes variable step lengths along F-actin tracks, adapting to angular disorder in the track structure.

The paper identifies Pericentrin-Like-Protein (PLP) as a Kinesin-1 activator that drives centriole motility during interphase.

This study identifies a mutation in MYO15 that disrupts actin nucleation at stereocilia tips, causing hearing loss by impairing stereocilia growth.

The paper identifies a gene duplication in Ashbya gossypii that generates two septin proteins with distinct biophysical properties and developmental regulation.

The paper shows SMIFH2 inhibits myosin ATPase activity and actin filament translocation, affecting myosin 2A, myosin 10, and other non-muscle myosins, suggesting caution in using SMIFH2 to infer formin function.

This study identifies Src-dependent NM2A tyrosine-phosphorylation at residue 158 as a regulator of actomyosin dynamics and cell responses to bacterial infection.

This study discovers and characterizes skeletostatins, selective skeletal myosin II inhibitors with improved properties for research and drug development.

This study characterizes the ATPase mechanism of MYO15A, a motor protein involved in stereocilia development, and identifies its kinetic properties relevant to hearing loss.

This study shows that competition between kinesin-1 and myosin-V, influenced by cortical microtubule density, determines posterior localization of osk mRNA in Drosophila oocytes.

This paper introduces a method to mass-image single biomolecules in solution with high precision and resolution, enabling the study of molecular interactions and assemblies.

This study compares the motile and mechanical properties of NM-2A and NM-2B filaments, showing that NM2-A filaments require specific conditions to move processively.

This study presents a crystal structure of human nonmuscle myosin-2C and identifies an allosteric communication pathway that affects nucleotide binding and release kinetics.