HIV-1 initiates genomic RNA packaging in a unique subset of host RNA granules
M. Tanaka, B. C. Barajas, B. A. Robinson, D. J. Phuong, K. Chutiraka, J. C. Reed, J. R. Lingappa
This paper identifies the packaging initiation complex of HIV-1 genomic RNA as a co-opted host RNA granule and defines the two-step mechanism by which Gag enters this granule to initiate RNA packaging.
bioRxiv · Sep 6, 2017Microbiology