Caspase-mediated cleavage of murine norovirus NS1/2 potentiates apoptosis and is required for persistent infection of intestinal epithelial cells
B. A. Robinson, J. A. Van Winkle, B. T. McCune, A. M. Peters, T. J. Nice
This study shows that cleavage of NS1/2 by caspases in MNV-infected intestinal epithelial cells promotes apoptosis and is required for persistent infection, but not for acute infection in other cell types.
bioRxiv · Mar 26, 2019Microbiology