Pathogen evasion of chemokine response through suppression of CXCL10
A. L. Antonia, K. D. Gibbs, E. Trahair, K. J. Pittman, B. H. Schott, J. S. Smith, S. Rajagopal, J. W. Thompson, R. L. Reinhardt, D. C. Ko
This paper identifies a mechanism by which Leishmania major evades the immune system by cleaving CXCL10, a chemokine critical for T-cell recruitment, and shows similar strategies are used by other pathogens.
bioRxiv · Apr 29, 2019Microbiology