Multiparametric senescent cell phenotyping reveals CD24 osteolineage cells as targets of senolytic therapy in the aged murine skeleton
M. L. Doolittle, D. Saul, J. Kaur, J. L. Rowsey, S. J. Vos, K. D. Pavelko, J. N. Farr, D. Monroe, S. Khosla
The paper uses CyTOF to identify senescent mesenchymal cells in aged mice, finding CD24+ osteolineage cells as targets for senolytic therapy.
bioRxiv · Jan 12, 2023Cell Biology