An in vitro experimental pipeline to characterize the binding specificity of SARS-CoV-2 neutralizing antibodies
K. E. Atanasoff, L. Brambilla, D. C. Adelsberg, S. S. Kowdle, C. S. Stevens, C.-t. Hung, Y. Fu, R. Lim, L. Tran, R. Allen, J. A. Duty, G. Bajic, B. Lee, D. Tortorella
This paper characterizes the binding specificity and epitope of a broadly neutralizing anti-SARS-CoV-2 Spike RBD antibody using mAb-resistant virions and cryo-EM structural analysis.
bioRxiv · Apr 20, 2023 · PreprintMicrobiology