Author

J. A. Duty

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

B. Lee· 3 shared C.-t. Hung· 2 shared D. Tortorella· 2 shared R. Allen· 2 shared R. Lim· 2 shared S. S. Kowdle· 2 shared Y. Fu· 2 shared A. Garcia-Sastre· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersMicrobiology

B. Lee

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

De novo antibody discovery in human blood from full-length single B cell transcriptomics and matching haplotyped-resolved germline assemblies

J. Beaulaurier, L. Ly, J. A. Duty, C. Tyer, C. Stevens, C.-t. Hung, A. Sookdeo, A. W. Drong, S. Kowdle, D. J. Turner, S. Juul, S. Hickey, B. Lee

This study uses single-cell transcriptomics and germline haplotype assembly to discover antibodies from human blood post-MMR vaccination, showing neutralization of measles virus.

bioRxiv · Mar 26, 2024 · PreprintImmunology

An in vitro experimental pipeline to characterize the binding specificity of SARS-CoV-2 neutralizing antibodies

K. E. Atanasoff, L. Brambilla, D. C. Adelsberg, S. S. Kowdle, C. S. Stevens, C.-t. Hung, Y. Fu, R. Lim, L. Tran, R. Allen, J. A. Duty, G. Bajic, B. Lee, D. Tortorella

This paper characterizes the binding specificity and epitope of a broadly neutralizing anti-SARS-CoV-2 Spike RBD antibody using mAb-resistant virions and cryo-EM structural analysis.

bioRxiv · Apr 20, 2023 · PreprintMicrobiology

Discovery of a SARS-CoV-2 Broadly-Acting Neutralizing Antibody with Activity against Omicron and Omicron + R346K Variants

J. A. Duty, T. A. Kraus, H. Zhou, Y. Zhang, N. Shaabani, S. Yildiz, N. Du, A. Singh, L. Miorin, D. Li, K. Stegman, S. I. Ophir, X. Cao, K. Atanasoff, R. Lim, , R. Allen

This paper identifies a broadly neutralizing antibody, STI-9167, effective against SARS-CoV-2 variants including Omicron and Omicron + R346K, and describes its development for clinical trials.

bioRxiv · Jan 19, 2022 · PreprintMicrobiology