Author

L. Brambilla

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

B. Lee· 2 shared C. S. Stevens· 2 shared C.-t. Hung· 2 shared A. Arnett· 1 shared A. Gowlikar· 1 shared A. Pessina· 1 shared A. Wegner· 1 shared B. Khor· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersMicrobiology

B. Lee

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

An in vitro experimental pipeline to characterize the binding specificity of SARS-CoV-2 neutralizing antibodies

K. E. Atanasoff, L. Brambilla, D. C. Adelsberg, S. S. Kowdle, C. S. Stevens, C.-t. Hung, Y. Fu, R. Lim, L. Tran, R. Allen, J. A. Duty, G. Bajic, B. Lee, D. Tortorella

This paper characterizes the binding specificity and epitope of a broadly neutralizing anti-SARS-CoV-2 Spike RBD antibody using mAb-resistant virions and cryo-EM structural analysis.

bioRxiv · Apr 20, 2023 · PreprintMicrobiology

PGM3 inhibition Shows cooperative Effects With Erastin inducing Pancreatic cancer cell death via activation of the Unfolded Protein Response

B. Zerbato, M. Gobbi, T. Ludwig, V. Brancato, A. Pessina, L. Brambilla, A. Wegner, F. Chiaradonna

bioRxiv · Mar 19, 2023 · PreprintCancer Biology

Tonic interferon restricts pathogenic IL-17-driven inflammatory disease via balancing the microbiome

I. J. Marie, L. Brambilla, D. Azzouz, Z. Chen, G. V. Baracho, A. Arnett, H. S. Li, W. Liu, L. Cimmino, P. Chattopadhyay, G. Silverman, S. S. Watowich, B. Khor, D. Levy

This study shows that tonic interferon signaling maintains immune homeostasis by regulating gut microbiota, preventing IL-17-driven inflammation and myeloid hyperplasia in STAT1 KO mice.

bioRxiv · Apr 21, 2021Immunology

Alpha-1-antitrypsin and its variant-dependent role in COVID-19 pathogenesis

C. S. Stevens, K. Y. Oguntuyo, S. Kowdle, A. Gowlikar, M. N. Siddiquey, J. A. Acklin, G. Haas, R. M. Schilke, M. D. Woolard, H. Zhang, L. Brambilla, S. Ikegame, C.-t. Hung, J. K. Lim, R. W. Cross, , B. Lee

This study investigates the role of alpha-1-antitrypsin in inhibiting SARS-CoV-2 entry and shows variant-dependent effects on its ability to block different viral strains.

bioRxiv · Aug 14, 2020 · PreprintMicrobiology