Author

K. F. Leesch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

A. Pauli· 2 shared A. Beyer· 1 shared A. Chugunova· 1 shared A. Lackner· 1 shared A. Meinhart· 1 shared A. Smith· 1 shared A. von Haeseler· 1 shared C. Buecker· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

A. Pauli

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Author profile →

2 papers

Recent·Most cited

A molecular network of conserved factors keeps ribosomes dormant in the egg

K. F. Leesch, L. Lorenzo-Orts, C. Pribitzer, I. Grishkovskaya, M. Matzinger, E. Roitinger, K. Belacic, S. Kandolf, T.-Y. Lin, K. Mechtler, A. Meinhart, D. Haselbach, A. Pauli

The paper identifies conserved factors that maintain ribosome dormancy in zebrafish and Xenopus eggs and embryos, transitioning to an active state during early development.

bioRxiv · Nov 3, 2021Biochemistry

NMD is required for timely cell fate transitions by fine-tuning gene expression and controlling translation

E. Galimberti, R. Sehlke, M. Huth, M. Garmhausen, M. Romeike, J. Ramesmayer, S. Stummer, F. Titz-Teixeira, V. Herzog, A. Chugunova, K. F. Leesch, L. Holcik, L. Santini, A. Lackner, A. von Haeseler, , M. Leeb

This study shows NMD regulates cell fate transitions by controlling Eif4a2 translation and revealing a hierarchy in Smg5, Smg6, and Smg7 functions.

bioRxiv · Jul 7, 2020Cell Biology