Author

I. Grishkovskaya

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:cryo-EM· 2 Approach:microscopy & imaging analysis· 2 Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2

Frequent Co-Authors

K. Djinovic-Carugo· 3 shared A. Akalin· 2 shared D. Haselbach· 2 shared D. Slade· 2 shared K. Belacic· 2 shared K. Mechtler· 2 shared L.-M. Appel· 2 shared V. Franke· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersBiochemistry

K. Djinovic-Carugo

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5 papers

Recent·Most cited

Cryo-EM structure of the chain-elongating E3 ligase UBR5

Z. Hodakova, I. Grishkovskaya, H. L. Brunner, D. L. Bolhuis, K. Belacic, A. Schleiffer, H. Kotisch, N. G. Brown, D. Haselbach

The paper presents the cryo-EM structure of UBR5, revealing its dimeric architecture and dynamic domain movements, and identifies AKIRIN2 as an interacting protein.

bioRxiv · Nov 3, 2022 · PreprintBiochemistry

The SPOC domain is a phosphoserine binding module that bridges transcription machinery with co- and post-transcriptional regulators

L.-M. Appel, I. Grishkovskaya, J. Benedum, V. Franke, A. Polyansky, A. Neudolt, A. Wunder, B. Zagrovic, A. Akalin, K. Djinovic-Carugo, D. Slade

bioRxiv · Feb 26, 2022 · PreprintBiochemistry

A molecular network of conserved factors keeps ribosomes dormant in the egg

K. F. Leesch, L. Lorenzo-Orts, C. Pribitzer, I. Grishkovskaya, M. Matzinger, E. Roitinger, K. Belacic, S. Kandolf, T.-Y. Lin, K. Mechtler, A. Meinhart, D. Haselbach, A. Pauli

The paper identifies conserved factors that maintain ribosome dormancy in zebrafish and Xenopus eggs and embryos, transitioning to an active state during early development.

bioRxiv · Nov 3, 2021Biochemistry

Structures of three MORN repeat proteins and a re-evaluation of the proposed lipid-binding properties of MORN repeats

S. Sajko, I. Grishkovskaya, J. Kostan, M. Graewert, K. Setiawan, L. Truebestein, K. Niedermuller, C. Gehin, A. Sponga, M. Puchinger, A.-C. Gavin, T. Leonard, D. I. Svergun, T. K. Smith, B. C. Morriswood, K. Djinovic-Carugo

This study investigates MORN repeat proteins, revealing they are protein-protein interaction modules rather than lipid-binding modules, based on structural and functional analyses of TbMORN1 and homologs.

bioRxiv · Jun 23, 2020Biochemistry

PHF3 regulates neuronal gene expression through the new Pol II CTD reader domain SPOC

L.-M. Appel, V. Franke, M. Bruno, I. Grishkovskaya, A. Kasiliauskaite, U. E. Schoeberl, M. G. Puchinger, S. Kostrhon, E. Beltzung, K. Mechtler, G. Lin, A. Vlasova, M. Leeb, R. Pavri, A. Stark, , D. Slade

This study identifies PHF3 as a CTD-binding factor that regulates neuronal gene expression by inhibiting Pol II elongation and mRNA stability.

bioRxiv · Feb 11, 2020Biochemistry