Insulin resistance in cavefish as an adaptation to a nutrient-limited environment
A. Aspiras, M. Riddle, K. Gaudenz, R. Peuss, J. Sung, B. Martineau, M. Peavey, A. Box, J. A. Tabin, S. McGaugh, R. Borowsky, C. J. Tabin, N. Rohner
This study shows cavefish have insulin resistance due to a mutation in the insulin receptor, which may confer advantages in nutrient-limited environments despite negative effects seen in humans.
bioRxiv · Aug 21, 2017Evolutionary Biology