Traumatic Joint Injury Induces Acute Catabolic Bone Turnover Concurrent with Articular Cartilage Damage in a Rat Model of Post-Traumatic Osteoarthritis
T. Maerz, M. D. Newton, M. Fleischer, S. E. Hartner, K. Gawronski, L. Junginger, K. C. Baker
This study shows that traumatic joint injury in rats causes acute bone catabolism and cartilage damage, with reduced bone formation and increased osteoclast activity.
bioRxiv · Apr 10, 2020Physiology